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Modeling Na(+)-Ca(2+) exchange in the heart: allosteric activation, spatial localization, sparks and excitation-contraction coupling

The cardiac sodium (Na(+))/calcium (Ca(2+)) exchanger (NCX1) is an electrogenic membrane transporter that regulates Ca(2+) homeostasis in cardiomyocytes, serving mainly to extrude Ca(2+) during diastole. The direction of Ca(2+) transport reverses at membrane potentials near that of the action potent...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Cell Cardiol
Egile Nagusiak: Chu, Lulu, Greenstein, Joseph L., Winslow, Raimond L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534334/
https://ncbi.nlm.nih.gov/pubmed/27377851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.06.068
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