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Effect of carvedilol on atrial excitation-contraction coupling, Ca(2+) release, and arrhythmogenicity

Carvedilol is an FDA-approved β-blocker commonly used for treatment of high blood pressure, congestive heart failure, and cardiac tachyarrhythmias, including atrial fibrillation. We investigated at the cellular level the mechanisms through which carvedilol interferes with sarcoplasmic reticulum (SR)...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Heart Circ Physiol
Main Authors: Martinez-Hernandez, E., Blatter, L. A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7395480/
https://ncbi.nlm.nih.gov/pubmed/32275472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00650.2019
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