Differential Regulation of Self-reactive CD4(+) T Cells in Cervical Lymph Nodes and Central Nervous System during Viral Encephalomyelitis

Viral infections have long been implicated as triggers of autoimmune diseases, including multiple sclerosis (MS), a central nervous system (CNS) inflammatory demyelinating disorder. Epitope spreading, molecular mimicry, cryptic antigen, and bystander activation have been implicated as mechanisms res...

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Publicado en:Front Immunol
Autores principales: Savarin, Carine, Bergmann, Cornelia C., Hinton, David R., Stohlman, Stephen A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030268/
https://ncbi.nlm.nih.gov/pubmed/27708643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00370
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