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Self-reactive CD4(+) T cells activated during viral-induced demyelination do not prevent clinical recovery

BACKGROUND: Microbial infections have been implicated in initiating and enhancing severity of autoimmune diseases including the demyelinating disease multiple sclerosis (MS). Nevertheless, the incidence of both acute and persisting viral infections without evidence of autoimmune sequelae suggests th...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Savarin, Carine, Bergmann, Cornelia C., Gaignage, Melanie, Stohlman, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642610/
https://ncbi.nlm.nih.gov/pubmed/26559484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0426-1
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