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Self-reactive CD4(+) T cells activated during viral-induced demyelination do not prevent clinical recovery

BACKGROUND: Microbial infections have been implicated in initiating and enhancing severity of autoimmune diseases including the demyelinating disease multiple sclerosis (MS). Nevertheless, the incidence of both acute and persisting viral infections without evidence of autoimmune sequelae suggests th...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Savarin, Carine, Bergmann, Cornelia C., Gaignage, Melanie, Stohlman, Stephen A.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4642610/
https://ncbi.nlm.nih.gov/pubmed/26559484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0426-1
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