Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein

Hepatocellular carcinoma (HCC), an aggressive and the fastest growing life-threatening cancer worldwide, is often diagnosed at intermediate or advanced stages of the disease, which substantially limits therapeutic approaches for its successful treatment. This indicates that the prevention of hepatoc...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Ortega, Juliana F., de Conti, Aline, Tryndyak, Volodymyr, Furtado, Kelly S., Heidor, Renato, Horst, Maria Aderuza, Fernandes, Laura Helena Gasparini, Tavares, Paulo Eduardo Latorre Martins, Pogribna, Marta, Shpyleva, Svitlana, Beland, Frederick A., Pogribny, Igor P., Moreno, Fernando Salvador
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029705/
https://ncbi.nlm.nih.gov/pubmed/27013579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8248
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