Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein

Hepatocellular carcinoma (HCC), an aggressive and the fastest growing life-threatening cancer worldwide, is often diagnosed at intermediate or advanced stages of the disease, which substantially limits therapeutic approaches for its successful treatment. This indicates that the prevention of hepatoc...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ortega, Juliana F., de Conti, Aline, Tryndyak, Volodymyr, Furtado, Kelly S., Heidor, Renato, Horst, Maria Aderuza, Fernandes, Laura Helena Gasparini, Tavares, Paulo Eduardo Latorre Martins, Pogribna, Marta, Shpyleva, Svitlana, Beland, Frederick A., Pogribny, Igor P., Moreno, Fernando Salvador
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029705/
https://ncbi.nlm.nih.gov/pubmed/27013579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8248
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