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PIM1 destabilization activates a p53-dependent response to ribosomal stress in cancer cells
Defects in ribosome biogenesis triggers a stress response (ribosomal stress) that can lead to growth arrest and apoptosis. Signaling pathways activated by ribosomal stress are specifically involved in the pathological mechanism of a group of disorders defined as ribosomopathies. However, more genera...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5029667/ https://ncbi.nlm.nih.gov/pubmed/26993775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8070 |
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