Androgen deprivation therapy sensitizes triple negative breast cancer cells to immune-mediated lysis through androgen receptor independent modulation of osteoprotegerin

Among breast cancer types, triple-negative breast cancer (TNBC) has the fewest treatment options and the lowest 5-year survival rate. Androgen receptor (AR) inhibition has displayed efficacy against breast cancer preclinically and is currently being examined clinically in AR positive TNBC patients....

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Vydáno v:Oncotarget
Hlavní autoři: Kwilas, Anna R., Ardiani, Andressa, Gameiro, Sofia R., Richards, Jacob, Hall, Ashley B., Hodge, James W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029642/
https://ncbi.nlm.nih.gov/pubmed/27015557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8274
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