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Radiation-induced survival responses promote immunogenic modulation to enhance immunotherapy in combinatorial regimens

Tumor cells that survive radiation are more sensitive to T-cell-mediated lysis due to a spectrum of biological adaptations to cellular stress (defined as immunogenic modulation), including enhanced antigen processing and cell-surface presence of calreticulin. This mechanism can be exploited to maxim...

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מידע ביבליוגרפי
Main Authors: Gameiro, Sofia R, Ardiani, Andressa, Kwilas, Anna, Hodge, James W
פורמט: Artigo
שפה:Inglês
יצא לאור: Landes Bioscience 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091054/
https://ncbi.nlm.nih.gov/pubmed/25097803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28643
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