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Radiation-induced survival responses promote immunogenic modulation to enhance immunotherapy in combinatorial regimens
Tumor cells that survive radiation are more sensitive to T-cell-mediated lysis due to a spectrum of biological adaptations to cellular stress (defined as immunogenic modulation), including enhanced antigen processing and cell-surface presence of calreticulin. This mechanism can be exploited to maxim...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091054/ https://ncbi.nlm.nih.gov/pubmed/25097803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28643 |
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