Improving clinical benefit for prostate cancer patients through the combination of androgen deprivation and immunotherapy

Androgen-deprivation therapy (ADT) induces prostate cancer immunogenic modulation (IM) by reducing human tumor cell expression of anti-apoptotic genes thus facilitating increased sensitivity to immune-mediated lysis. Through its stimulation of IM, ADT has been shown to synergize with active immunoth...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Kwilas, Anna R, Gameiro, Sofia R, Kim, Peter S, Malamas, Anthony S, Hodge, James W
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485836/
https://ncbi.nlm.nih.gov/pubmed/26155431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1009303
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