Tumor growth suppressive effect of IL-4 through p21-mediated activation of STAT6 in IL-4Rα overexpressed melanoma models

To evaluate the significance of interleukin 4 (IL-4) in tumor development, we compared B16F10 melanoma growth in IL-4-overespressing transgenic mice (IL-4 mice) and non-transgenic mice. In IL-4 mice, reduced tumor volume and weight were observed when compared with those of non-transgenic mice. Signi...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Lee, Hye Lim, Park, Mi Hee, Song, Ju Kyoung, Jung, Yu Yeon, Kim, Youngsoo, Kim, Kyung Bo, Hwang, Dae Yeon, Yoon, Do Young, Song, Min Jong, Han, Sang Bae, Hong, Jin Tae
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029637/
https://ncbi.nlm.nih.gov/pubmed/26993600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8111
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