Tumor growth suppressive effect of IL-4 through p21-mediated activation of STAT6 in IL-4Rα overexpressed melanoma models

To evaluate the significance of interleukin 4 (IL-4) in tumor development, we compared B16F10 melanoma growth in IL-4-overespressing transgenic mice (IL-4 mice) and non-transgenic mice. In IL-4 mice, reduced tumor volume and weight were observed when compared with those of non-transgenic mice. Signi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Lee, Hye Lim, Park, Mi Hee, Song, Ju Kyoung, Jung, Yu Yeon, Kim, Youngsoo, Kim, Kyung Bo, Hwang, Dae Yeon, Yoon, Do Young, Song, Min Jong, Han, Sang Bae, Hong, Jin Tae
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029637/
https://ncbi.nlm.nih.gov/pubmed/26993600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8111
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