IL-32 gamma reduces lung tumor development through upregulation of TIMP-3 overexpression and hypomethylation

The low expression of tissue inhibitor of metalloproteinase 3 (TIMP-3) is important in inflammatory responses. Therefore, inhibition of TIMP-3 may promote tumor development. Our study showed that expression of TIMP-3 was elevated in lL-32γ mice lung tissues. In this study, we investigated whether IL...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Yun, Jaesuk, Park, Mi Hee, Son, Dong Ju, Nam, Kyung Tak, Moon, Dae Bong, Ju, Jung Heun, Hwang, Ok Kyung, Choi, Jeong Soon, Kim, Tae Hoon, Jung, Young Suk, Hwang, Dae Yeon, Han, Sang Bae, Yoon, Do-Young, Hong, Jin Tae
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833366/
https://ncbi.nlm.nih.gov/pubmed/29467412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0375-6
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