Double-strand break repair and colorectal cancer: gene variants within 3′ UTRs and microRNAs binding as modulators of cancer risk and clinical outcome

Genetic variations in 3′ untranslated regions of target genes may affect microRNA binding, resulting in differential protein expression. microRNAs regulate DNA repair, and single-nucleotide polymorphisms in miRNA binding sites (miRSNPs) may account for interindividual differences in the DNA repair c...

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Publicado en:Oncotarget
Autores principales: Naccarati, Alessio, Rosa, Fabio, Vymetalkova, Veronika, Barone, Elisa, Jiraskova, Katerina, Di Gaetano, Cornelia, Novotny, Jan, Levy, Miroslav, Vodickova, Ludmila, Gemignani, Federica, Buchler, Tomas, Landi, Stefano, Vodicka, Pavel, Pardini, Barbara
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029617/
https://ncbi.nlm.nih.gov/pubmed/26735576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6804
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