Double-strand break repair and colorectal cancer: gene variants within 3′ UTRs and microRNAs binding as modulators of cancer risk and clinical outcome

Genetic variations in 3′ untranslated regions of target genes may affect microRNA binding, resulting in differential protein expression. microRNAs regulate DNA repair, and single-nucleotide polymorphisms in miRNA binding sites (miRSNPs) may account for interindividual differences in the DNA repair c...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Naccarati, Alessio, Rosa, Fabio, Vymetalkova, Veronika, Barone, Elisa, Jiraskova, Katerina, Di Gaetano, Cornelia, Novotny, Jan, Levy, Miroslav, Vodickova, Ludmila, Gemignani, Federica, Buchler, Tomas, Landi, Stefano, Vodicka, Pavel, Pardini, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029617/
https://ncbi.nlm.nih.gov/pubmed/26735576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6804
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