Functional Polymorphisms in DNA Repair Genes Are Associated with Sporadic Colorectal Cancer Susceptibility and Clinical Outcome

DNA repair processes are involved in both the onset and treatment efficacy of colorectal cancer (CRC). A change of a single nucleotide causing an amino acid substitution in the corresponding protein may alter the efficiency of DNA repair, thus modifying the CRC susceptibility and clinical outcome. W...

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Udgivet i:Int J Mol Sci
Main Authors: Jiraskova, Katerina, Hughes, David J., Brezina, Stefanie, Gumpenberger, Tanja, Veskrnova, Veronika, Buchler, Tomas, Schneiderova, Michaela, Levy, Miroslav, Liska, Vaclav, Vodenkova, Sona, Di Gaetano, Cornelia, Naccarati, Alessio, Pardini, Barbara, Vymetalkova, Veronika, Gsur, Andrea, Vodicka, Pavel
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337670/
https://ncbi.nlm.nih.gov/pubmed/30591675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20010097
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