Telomere length predicts replicative capacity of human fibroblasts.

When human fibroblasts from different donors are grown in vitro, only a small fraction of the variation in their finite replicative capacity is explained by the chronological age of the donor. Because we had previously shown that telomeres, the terminal guanine-rich sequences of chromosomes, shorten...

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Библиографические подробности
Главные авторы: Allsopp, R C, Vaziri, H, Patterson, C, Goldstein, S, Younglai, E V, Futcher, A B, Greider, C W, Harley, C B
Формат: Artigo
Язык:Inglês
Опубликовано: 1992
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC50288/
https://ncbi.nlm.nih.gov/pubmed/1438199
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