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Excision of 5-hydroxymethylcytosine by DEMETER family DNA glycosylases
In plants and animals, 5-methylcytosine (5mC) serves as an epigenetic mark to repress gene expression, playing critical roles for cellular differentiation and transposon silencing. Mammals also have 5-hydroxymethylcytosine (5hmC), resulting from hydroxylation of 5mC by TET family-enzymes. 5hmC is ab...
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| Udgivet i: | Biochem Biophys Res Commun |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5028334/ https://ncbi.nlm.nih.gov/pubmed/24661881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.03.060 |
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