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Domain structure of the DEMETER 5-methylcytosine DNA glycosylase

DNA glycosylases initiate the base excision repair (BER) pathway by excising damaged, mismatched, or otherwise modified bases. Animals and plants independently evolved active BER-dependent DNA demethylation mechanisms important for epigenetic reprogramming. One such DNA demethylation mechanism is un...

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Detalhes bibliográficos
Main Authors: Mok, Young Geun, Uzawa, Rie, Lee, Jiyoon, Weiner, Gregory M., Eichman, Brandt F., Fischer, Robert L., Huh, Jin Hoe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984145/
https://ncbi.nlm.nih.gov/pubmed/20974931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014348107
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