AP endonucleases process 5-methylcytosine excision intermediates during active DNA demethylation in Arabidopsis

DNA methylation is a primary epigenetic modification regulating gene expression and chromatin structure in many eukaryotes. Plants have a unique DNA demethylation system in that 5-methylcytosine (5mC) is directly removed by DNA demethylases, such as DME/ROS1 family proteins, but little is known abou...

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Bibliographic Details
Main Authors: Lee, Jiyoon, Jang, Hosung, Shin, Hosub, Choi, Woo Lee, Mok, Young Geun, Huh, Jin Hoe
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191409/
https://ncbi.nlm.nih.gov/pubmed/25228464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku834
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