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Inflammation as a Driver and Vulnerability of KRAS Mediated Oncogenesis

While important strides have been made in cancer therapy by targeting certain oncogenes, KRAS, the most common among them, remains refractory to this approach. In recent years, a deeper understanding of the critical importance of inflammation in promoting KRAS-driven oncogenesis has emerged, and app...

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Detalhes bibliográficos
Publicado no:Semin Cell Dev Biol
Main Authors: Kitajima, Shunsuke, Thummalapalli, Rohit, Barbie, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028268/
https://ncbi.nlm.nih.gov/pubmed/27297136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2016.06.009
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