Llwytho...
Engineering the metamorphic chemokine Lymphotactin/XCL1 into the GAG-binding, HIV-inhibitory dimer conformation
Unlike other chemokines, XCL1 undergoes a distinct metamorphic interconversion between a canonical monomeric chemokine fold and a unique β-sandwich dimer. The monomeric conformation binds and activates the receptor XCR1, while the dimer binds extracellular matrix glycosaminoglycans and has been asso...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | ACS Chem Biol |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2015
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5028202/ https://ncbi.nlm.nih.gov/pubmed/26302421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00542 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|