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Chemical Inhibitors of Non-Homologous End Joining Increase Targeted Construct Integration in Cryptococcus neoformans

The development of a biolistic transformation protocol for Cryptococcus neoformans over 25 years ago ushered in a new era of molecular characterization of virulence in this previously intractable fungal pathogen. However, due to the low rate of homologous recombination in this species, the process o...

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Publicat a:PLoS One
Autors principals: Arras, Samantha D. M., Fraser, James A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028063/
https://ncbi.nlm.nih.gov/pubmed/27643854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163049
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