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Chemical Inhibitors of Non-Homologous End Joining Increase Targeted Construct Integration in Cryptococcus neoformans

The development of a biolistic transformation protocol for Cryptococcus neoformans over 25 years ago ushered in a new era of molecular characterization of virulence in this previously intractable fungal pathogen. However, due to the low rate of homologous recombination in this species, the process o...

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Pubblicato in:PLoS One
Autori principali: Arras, Samantha D. M., Fraser, James A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028063/
https://ncbi.nlm.nih.gov/pubmed/27643854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163049
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