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Staufen1s role as a splicing factor and a disease modifier in Myotonic Dystrophy Type I

In a recent issue of PLOS Genetics, we reported that the double-stranded RNA-binding protein, Staufen1, functions as a disease modifier in the neuromuscular disorder Myotonic Dystrophy Type I (DM1). In this work, we demonstrated that Staufen1 regulates the alternative splicing of exon 11 of the huma...

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Detalhes bibliográficos
Publicado no:Rare Dis
Main Authors: Bondy-Chorney, Emma, Crawford Parks, Tara E., Ravel-Chapuis, Aymeric, Jasmin, Bernard J., Côté, Jocelyn
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027583/
https://ncbi.nlm.nih.gov/pubmed/27695661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21675511.2016.1225644
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