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Overexpression of Staufen1 in DM1 mouse skeletal muscle exacerbates dystrophic and atrophic features

In myotonic dystrophy type 1 (DM1), the CUG expansion (CUG(exp)) in the 3′ untranslated region of the dystrophia myotonica protein kinase messenger ribonucleic acid affects the homeostasis of ribonucleic acid-binding proteins, causing the multiple symptoms of DM1. We have previously reported that St...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Crawford Parks, Tara E, Marcellus, Kristen A, Péladeau, Christine, Jasmin, Bernard J, Ravel-Chapuis, Aymeric
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399530/
https://ncbi.nlm.nih.gov/pubmed/32504084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa111
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