The RNA-binding protein Staufen1 is increased in DM1 skeletal muscle and promotes alternative pre-mRNA splicing

Eitemau Tebyg

• Staufen1 Regulates Multiple Alternative Splicing Events either Positively or Negatively in DM1 Indicating Its Role as a Disease Modifier
  gan: Bondy-Chorney, Emma, et al.
  Cyhoeddwyd: (2016)
• Staufen1s role as a splicing factor and a disease modifier in Myotonic Dystrophy Type I
  gan: Bondy-Chorney, Emma, et al.
  Cyhoeddwyd: (2016)
• Overexpression of Staufen1 in DM1 mouse skeletal muscle exacerbates dystrophic and atrophic features
  gan: Crawford Parks, Tara E, et al.
  Cyhoeddwyd: (2020)
• Staufen1 impairs stress granule formation in skeletal muscle cells from myotonic dystrophy type 1 patients
  gan: Ravel-Chapuis, Aymeric, et al.
  Cyhoeddwyd: (2016)
• A genome-wide approach identifies distinct but overlapping subsets of cellular mRNAs associated with Staufen1- and Staufen2-containing ribonucleoprotein complexes
  gan: Furic, Luc, et al.
  Cyhoeddwyd: (2008)