The Pch2 AAA+ ATPase promotes phosphorylation of the Hop1 meiotic checkpoint adaptor in response to synaptonemal complex defects

Meiotic cells possess surveillance mechanisms that monitor critical events such as recombination and chromosome synapsis. Meiotic defects resulting from the absence of the synaptonemal complex component Zip1 activate a meiosis-specific checkpoint network resulting in delayed or arrested meiotic prog...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Herruzo, Esther, Ontoso, David, González-Arranz, Sara, Cavero, Santiago, Lechuga, Ana, San-Segundo, Pedro A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027488/
https://ncbi.nlm.nih.gov/pubmed/27257060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw506
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