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Dot1-Dependent Histone H3K79 Methylation Promotes Activation of the Mek1 Meiotic Checkpoint Effector Kinase by Regulating the Hop1 Adaptor

During meiosis, accurate chromosome segregation relies on the proper interaction between homologous chromosomes, including synapsis and recombination. The meiotic recombination checkpoint is a quality control mechanism that monitors those crucial events. In response to defects in synapsis and/or rec...

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Detalhes bibliográficos
Main Authors: Ontoso, David, Acosta, Isabel, van Leeuwen, Fred, Freire, Raimundo, San-Segundo, Pedro A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561090/
https://ncbi.nlm.nih.gov/pubmed/23382701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003262
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