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DOT-1.1-dependent H3K79 methylation promotes normal meiotic progression and meiotic checkpoint function in C. elegans

Epigenetic modifiers are emerging as important regulators of the genome. However, how they regulate specific processes during meiosis is not well understood. Methylation of H3K79 by the histone methyltransferase Dot1 has been shown to be involved in the maintenance of genomic stability in various or...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Lascarez-Lagunas, Laura I., Herruzo, Esther, Grishok, Alla, San-Segundo, Pedro A., Colaiácovo, Mónica P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644094/
https://ncbi.nlm.nih.gov/pubmed/33104701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009171
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