An epigenetic switch regulates de novo DNA methylation at a subset of pluripotency gene enhancers during embryonic stem cell differentiation

Coordinated regulation of gene expression that involves activation of lineage specific genes and repression of pluripotency genes drives differentiation of embryonic stem cells (ESC). For complete repression of pluripotency genes during ESC differentiation, chromatin at their enhancers is silenced b...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Petell, Christopher J., Alabdi, Lama, He, Ming, San Miguel, Phillip, Rose, Richard, Gowher, Humaira
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Gene regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027477/
https://ncbi.nlm.nih.gov/pubmed/27179026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw426
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars