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NADPH oxidase-derived H(2)O(2) subverts pathogen signaling by oxidative phosphotyrosine conversion to PB-DOPA

Strengthening the host immune system to fully exploit its potential as antimicrobial defense is vital in countering antibiotic resistance. Chemical compounds released during bidirectional host–pathogen cross-talk, which follows a sensing-response paradigm, can serve as protective mediators. A potent...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Alvarez, Luis A., Kovačič, Lidija, Rodríguez, Javier, Gosemann, Jan-Hendrik, Kubica, Malgorzata, Pircalabioru, Gratiela G., Friedmacher, Florian, Cean, Ada, Ghişe, Alina, Sărăndan, Mihai B., Puri, Prem, Daff, Simon, Plettner, Erika, von Kriegsheim, Alex, Bourke, Billy, Knaus, Ulla G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027431/
https://ncbi.nlm.nih.gov/pubmed/27562167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605443113
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