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Mucosal reactive oxygen species decrease virulence by disrupting Campylobacter jejuni phosphotyrosine signaling

Reactive oxygen species (ROS) play key roles in mucosal defense, yet how they are induced and the consequences for pathogens are unclear. We report that ROS generated by epithelial NADPH oxidases (Nox1/Duox2) during Campylobacter jejuni infection impair bacterial capsule formation and virulence by a...

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Detalhes bibliográficos
Main Authors: Corcionivoschi, Nicolae, Alvarez, Luis A., Sharp, Thomas H., Strengert, Monika, Alemka, Abofu, Mantell, Judith, Verkade, Paul, Knaus, Ulla G., Bourke, Billy
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749511/
https://ncbi.nlm.nih.gov/pubmed/22817987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.05.018
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