Zinc-sensitive MRI contrast agent detects differential release of Zn(II) ions from the healthy vs. malignant mouse prostate

Many secretory tissues release Zn(II) ions along with other molecules in response to external stimuli. Here we demonstrate that secretion of Zn(II) ions from normal, healthy prostate tissue is stimulated by glucose in fasted mice and that release of Zn(II) can be monitored by MRI. An ∼50% increase i...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Clavijo Jordan, M. Veronica, Lo, Su-Tang, Chen, Shiuhwei, Preihs, Christian, Chirayil, Sara, Zhang, Shanrong, Kapur, Payal, Li, Wen-Hong, De Leon-Rodriguez, Luis M., Lubag, Angelo J. M., Rofsky, Neil M., Sherry, A. Dean
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027418/
https://ncbi.nlm.nih.gov/pubmed/27562169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609450113
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