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Amplifying the Sensitivity of Zinc(II) Responsive MRI Contrast Agents by Altering Water Exchange Rates
Given the known water exchange rate limitations of a previously reported Zn(II)-sensitive MRI contrast agent, GdDOTA-diBPEN, new structural targets were rationally designed to increase the rate of water exchange to improve MRI detection sensitivity. These new sensors exhibit fine-tuned water exchang...
में बचाया:
में प्रकाशित: | J Am Chem Soc |
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मुख्य लेखकों: | , , , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2015
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5796656/ https://ncbi.nlm.nih.gov/pubmed/26462412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b09158 |
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