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Structure of inositol monophosphatase, the putative target of lithium therapy.

Inositol monophosphatase (EC 3.1.3.25), the putative molecular site of action of lithium therapy for manic-depressive illness, plays a key role in the phosphatidylinositol signaling pathway by catalyzing the hydrolysis of inositol monophosphates. To provide a structural basis from which to design be...

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Détails bibliographiques
Auteurs principaux: Bone, R, Springer, J P, Atack, J R
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC50271/
https://ncbi.nlm.nih.gov/pubmed/1332026
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