Structure of inositol monophosphatase, the putative target of lithium therapy.
Inositol monophosphatase (EC 3.1.3.25), the putative molecular site of action of lithium therapy for manic-depressive illness, plays a key role in the phosphatidylinositol signaling pathway by catalyzing the hydrolysis of inositol monophosphates. To provide a structural basis from which to design be...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1992
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50271/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1332026/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.21.10031 |
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