Imaging of cerebral α(4)β(2)* nicotinic acetylcholine receptors with (−)-[(18)F]Flubatine PET: Implementation of bolus plus constant infusion and sensitivity to acetylcholine in human brain()

The positron emission tomography (PET) radioligand (−)-[(18)F]flubatine is specific to [Formula: see text] nicotinic acetylcholine receptors (nAChRs) and has promise for future investigation of the acetylcholine system in neuropathologies such as Alzheimer's disease, schizophrenia, and substanc...

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Publicat a:Neuroimage
Autors principals: Hillmer, A.T., Esterlis, I., Gallezot, J.D., Bois, F., Zheng, M.Q., Nabulsi, N., Lin, S.F., Papke, R.L., Huang, Y., Sabri, O., Carson, R.E., Cosgrove, K.P.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026941/
https://ncbi.nlm.nih.gov/pubmed/27426839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2016.07.026
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