Elevated intracellular pH appears in aged oocytes and causes oocyte aneuploidy associated with the loss of cohesion in mice

Increases in the aneuploidy rate caused by the deterioration of cohesion with increasing maternal age have been well documented. However, the molecular mechanism for the loss of cohesion in aged oocytes remains unknown. In this study, we found that intracellular pH (pH(i)) was elevated in aged oocyt...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell Cycle
Κύριοι συγγραφείς: Cheng, Jin-Mei, Li, Jian, Tang, Ji-Xin, Chen, Su-Ren, Deng, Shou-Long, Jin, Cheng, Zhang, Yan, Wang, Xiu-Xia, Zhou, Chen-Xi, Liu, Yi-Xun
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Taylor & Francis 2016
Θέματα:
Report
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026820/
https://ncbi.nlm.nih.gov/pubmed/27472084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1201255
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