Phosphorylation of Tyr188 in the WW domain of YAP1 plays an essential role in YAP1-induced cellular transformation

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. The pivotal effector of this pathway is YAP1, a transcriptional co-activator amplified in mouse and human cancers where it promotes epithelial-to-mesenchym...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Li, Ying-Wei, Guo, Jin, Shen, He, Li, Jun, Yang, Nuo, Frangou, Costa, Wilson, Kayla E., Zhang, Yinglong, Mussell, Ashley L., Sudol, Marius, Farooq, Amjad, Qu, Jun, Zhang, Jianmin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026814/
https://ncbi.nlm.nih.gov/pubmed/27428284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1207836
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