Therapeutic index estimation of antiepileptic drugs: a systematic literature review approach

OBJECTIVES: To determine whether data obtained from the medical literature can be used to estimate the therapeutic index of 5 antiepileptic drugs (AEDs): carbamazepine, lamotrigine, phenobarbital, phenytoin, and valproate. METHODS: We performed a literature search using PubMed and Embase to collect...

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Publicado en:Clin Neuropharmacol
Main Authors: Greenberg, Rachel G., Melloni, Chiara, Wu, Huali, Gonzalez, Daniel, Ku, Lawrence, Hill, Kevin D., Hornik, Christoph P., Zheng, Nan, Jiang, Wenlei, Cohen-Wolkowiez, Michael, Guptill, Jeffrey T.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026556/
https://ncbi.nlm.nih.gov/pubmed/27428884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNF.0000000000000172
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