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A systematic literature review approach to estimate the therapeutic index of selected immunosuppressant drugs following renal transplantation

BACKGROUND: Drugs that exhibit close margins between therapeutic and toxic blood concentrations are considered to have a narrow therapeutic index (NTI). The Food and Drug Administration has proposed that NTI drugs should have more stringent bioequivalence standards for approval of generic formulatio...

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Detalhes bibliográficos
Publicado no:Ther Drug Monit
Main Authors: Ericson, Jessica E., Zimmerman, Kanecia O., Gonzalez, Daniel, Melloni, Chiara, Guptill, Jeffrey T., Hill, Kevin D., Wu, Huali, Cohen-Wolkowiez, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5235278/
https://ncbi.nlm.nih.gov/pubmed/28081041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000364
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