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A systematic literature review approach to estimate the therapeutic index of selected immunosuppressant drugs following renal transplantation
BACKGROUND: Drugs that exhibit close margins between therapeutic and toxic blood concentrations are considered to have a narrow therapeutic index (NTI). The Food and Drug Administration has proposed that NTI drugs should have more stringent bioequivalence standards for approval of generic formulatio...
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Publicado no: | Ther Drug Monit |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5235278/ https://ncbi.nlm.nih.gov/pubmed/28081041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FTD.0000000000000364 |
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