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Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation
The rapid and robust synthesis of polymers of adenosine diphosphate (ADP)-ribose (PAR) chains, primarily catalyzed by poly(ADP-ribose) polymerase 1 (PARP1), is crucial for cellular responses to DNA damage. However, the precise mechanisms through which PARP1 is activated and PAR is robustly synthesiz...
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出版年: | PLoS Biol |
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主要な著者: | , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026359/ https://ncbi.nlm.nih.gov/pubmed/27635653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002543 |
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