Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation

The rapid and robust synthesis of polymers of adenosine diphosphate (ADP)-ribose (PAR) chains, primarily catalyzed by poly(ADP-ribose) polymerase 1 (PARP1), is crucial for cellular responses to DNA damage. However, the precise mechanisms through which PARP1 is activated and PAR is robustly synthesiz...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Sun, Xin, Fu, Kai, Hodgson, Andrea, Wier, Eric M., Wen, Matthew G., Kamenyeva, Olena, Xia, Xue, Koo, Lily Y., Wan, Fengyi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026359/
https://ncbi.nlm.nih.gov/pubmed/27635653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002543
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