Direct Visualization of HIV-1 Replication Intermediates shows that Viral Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration

Direct visualization of HIV-1 replication would improve our understanding of the viral lifecycle. We adapted established technology and reagents to develop an imaging approach, ViewHIV, which allows evaluation of early HIV-1 replication intermediates, from reverse transcription to integration. These...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Chin, Christopher R., Perreira, Jill M., Savidis, George, Portmann, Jocelyn M., Aker, Aaron M., Feeley, Eric M., Smith, Miles C., Brass, Abraham L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026322/
https://ncbi.nlm.nih.gov/pubmed/26586435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.036
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