A carregar...
Excess of Deleterious Mutations around HLA Genes Reveals Evolutionary Cost of Balancing Selection
Deleterious mutations are expected to evolve under negative selection and are usually purged from the population. However, deleterious alleles segregate in the human population and some disease-associated variants are maintained at considerable frequencies. Here, we test the hypothesis that balancin...
Na minha lista:
| Publicado no: | Mol Biol Evol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026253/ https://ncbi.nlm.nih.gov/pubmed/27436009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw127 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|