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No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans

Non-African populations have experienced size reductions in the time since their split from West Africans, leading to the hypothesis that natural selection to remove weakly deleterious mutations has been less effective in the history of non-Africans. To test this hypothesis, we measured the per-geno...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Do, Ron, Balick, Daniel, Li, Heng, Adzhubei, Ivan, Sunyaev, Shamil, Reich, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310772/
https://ncbi.nlm.nih.gov/pubmed/25581429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3186
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