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Predicting Functional Effect of Human Missense Mutations Using PolyPhen-2

PolyPhen-2 (Polymorphism Phenotyping v2), available as software and via a Web server, predicts the possible impact of amino acid substitutions on the stability and function of human proteins using structural and comparative evolutionary considerations. It performs functional annotation of single-nuc...

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書目詳細資料
發表在:Curr Protoc Hum Genet
Main Authors: Adzhubei, Ivan, Jordan, Daniel M., Sunyaev, Shamil R.
格式: Artigo
語言:Inglês
出版: 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480630/
https://ncbi.nlm.nih.gov/pubmed/23315928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142905.hg0720s76
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