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Predicting Functional Effect of Human Missense Mutations Using PolyPhen-2
PolyPhen-2 (Polymorphism Phenotyping v2), available as software and via a Web server, predicts the possible impact of amino acid substitutions on the stability and function of human proteins using structural and comparative evolutionary considerations. It performs functional annotation of single-nuc...
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| I publikationen: | Curr Protoc Hum Genet |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4480630/ https://ncbi.nlm.nih.gov/pubmed/23315928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142905.hg0720s76 |
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