Identification of a Distinct Substrate-binding Domain in the Bacterial Cysteine Methyltransferase Effectors NleE and OspZ

The type III secretion system effector protein NleE from enteropathogenic Escherichia coli plays a key role in the inhibition of NF-κB activation during infection. NleE inactivates the ubiquitin chain binding activity of host proteins TAK1-binding proteins 2 and 3 (TAB2 and TAB3) by modifying the Np...

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Vydáno v:J Biol Chem
Hlavní autoři: Zhang, Ying, Mühlen, Sabrina, Oates, Clare V., Pearson, Jaclyn S., Hartland, Elizabeth L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025698/
https://ncbi.nlm.nih.gov/pubmed/27445336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.734079
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