The Type III Effectors NleE and NleB from Enteropathogenic E. coli and OspZ from Shigella Block Nuclear Translocation of NF-κB p65

Many bacterial pathogens utilize a type III secretion system to deliver multiple effector proteins into host cells. Here we found that the type III effectors, NleE from enteropathogenic E. coli (EPEC) and OspZ from Shigella, blocked translocation of the p65 subunit of the transcription factor, NF-κB...

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Autores principales: Newton, Hayley J., Pearson, Jaclyn S., Badea, Luminita, Kelly, Michelle, Lucas, Mark, Holloway, Gavan, Wagstaff, Kylie M., Dunstone, Michelle A., Sloan, Joan, Whisstock, James C., Kaper, James B., Robins-Browne, Roy M., Jans, David A., Frankel, Gad, Phillips, Alan D., Coulson, Barbara S., Hartland, Elizabeth L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869321/
https://ncbi.nlm.nih.gov/pubmed/20485572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000898
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